Which of the following is an indication to conduct a CT scan in a patient presenting with a seizure?

Conducting a CT scan in a patient with a seizure is particularly indicated in the case of a new onset seizure. This context allows healthcare providers to assess potential underlying causes, such as structural abnormalities, cerebral hemorrhage, or lesions that may not be apparent in patients with a known history of seizures. New onset seizures often raise concerns for acute intracranial processes that need immediate identification and intervention, especially if the seizure presents differently from the patient's typical seizure activity or if it occurs without any prior history of seizures.

While a history of seizures can provide context for the patient's clinical background, and the postictal state may yield useful information regarding the aftermath of a recent seizure, these aspects do not inherently necessitate a CT scan unless there are specific concerns regarding changes in the patient's condition. Existing medications typically pertain to the overall management of the patient but do not serve as a direct indication for imaging in the context of new seizure activity. Identifying a new seizure is critical in guiding urgent care decisions and diagnostic imaging.